Beneficence obliges researchers to design and conduct studies in ways that enhance potential benefits and reduce risks for participants. It requires careful assessment of physical, psychological, social and economic harms that could result from participation. When risks cannot be justified by expected benefits or knowledge gains, the study should not proceed. Therefore, the principle described in the stem is beneficence.
Option A:
Justice concerns fair distribution of research burdens and benefits across groups, such as avoiding exploitation of vulnerable populations. While important, it focuses on fairness rather than on maximising benefit and minimising harm for individual participants.
Option B:
Beneficence guides decisions about safeguards, such as counselling support or debriefing, and may require modifying or discontinuing procedures that prove more harmful than anticipated. This emphasis on balancing risks and benefits matches the stem exactly, making this option correct.
Option C:
Fidelity refers to maintaining trust and keeping promises to participants, such as respecting agreements about data use, but it does not directly express the risk–benefit focus.
Option D:
Anonymity means that even researchers cannot link data to individuals, which protects privacy but is only one aspect of minimising harm; it is not the overarching principle named here.
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